Immunotoxins
| Definition: |
Semisynthetic conjugates of various toxic molecules, including radioactive isotopes and bacterial or plant toxins, with specific immune substances such as immunoglobulins, monoclonal antibodies, and antigens. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect. |
| Notes: |
IM; coord with specific toxin (IM) + specific immune substance (NIM) |
| Also Called: |
Toxins, Chimeric,Targeted Toxins |
| Previously Indexed: |
Antibodies, Monoclonal (1982-1986),Antigens, Surface (1979-1986),Antitoxins (1966-1986),Cytotoxicity, Immunologic (1978-1986),Ricin (1978-1985) |
Immunotoxins Definitions and Terms
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