Thyronines
| Definition: |
A group of metabolites derived from THYROXINE and TRIIODOTHYRONINE via the peripheral enzymatic removal of iodines from the thyroxine nucleus. Thyronine is the thyroxine nucleus devoid of its four iodine atoms. |
| Also Called: |
Thyronine |
Thyronines Categories.
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Diiodothyronines - These metabolites of THYROXINE are formed by the deiodination of T3 or reverse T3. |
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Triiodothyronine - A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. |
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Triiodothyronine, Reverse - A metabolite of THYROXINE, formed by the peripheral enzymatic monodeiodination of T4 at the 5 position of the inner ring of the iodothyronine nucleus. |
Thyronines Definitions and Terms
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