Sorption Detoxification
| Definition: |
Elimination of toxic or biologically active substances from body fluids by interaction with a sorbent medium. The types of media include absorbents, adsorbents, ion-exchange materials, and complexing agents. Detoxification can be extracorporeal (hemodialysis, hemofiltration, hemoperfusion, plasmapheresis), or occur inside the body (enterosorption, peritoneal dialysis). |
| Notes: |
do not use /util except by MeSH definition; DF: SORPTION DETOX |
| Previously Indexed: |
Adsorption (1977-1982),Hemoperfusion (1983-1990) |
Sorption Detoxification Categories.
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Enterosorption - Adsorption of substances from the gastrointestinal tract onto an orally administered sorbent medium like activated charcoal. This technique is used to eliminate toxic and some biologically active substances and serves to modify the lipid and amino acid spectrum of the intestinal contents. |
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Hemoperfusion - Removal of toxins or metabolites from the circulation by the passing of blood, within a suitable extracorporeal circuit, over semipermeable microcapsules containing adsorbents (e.g., activated charcoal) or enzymes, other enzyme preparations (e.g., gel-entrapped microsomes, membrane-free enzymes bound to artificial carriers), or other adsorbents (e.g., various resins, albumin-conjugated agarose). |
Sorption Detoxification Definitions and Terms
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