Rats, Inbred Strains
| Definition: |
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding. |
| Notes: |
GEN or unspecified; prefer specifics; NIM when exper animal: no qualif; when IM, qualif permitted; do not forget also to check tag RATS: Manual 18.6.14, 22.36; X ref AUGUST RATS is seen often in Russian lit |
| Also Called: |
August Rats |
| Previously Indexed: |
Rats (1966-1971) |
Rats, Inbred Strains Categories.
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Rats, Inbred ACI |
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Rats, Inbred BB - A strain of Rattus norvegicus which is a model for spontaneous insulin-dependent diabetes mellitus (DIABETES MELLITUS, INSULIN-DEPENDENT). |
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Rats, Inbred BN |
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Rats, Inbred BUF |
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Rats, Inbred Dahl - Inbred rats derived from Sprague-Dawley rats and used for the study of salt-dependent hypertension. Salt-sensitive and salt-resistant strains have been selectively bred to show the opposite genetically determined blood pressure responses to excess sodium chloride ingestion. |
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Rats, Inbred F344 |
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Rats, Inbred LEC - A cinnamon-colored strain of Long-Evans rats which carries a mutation causing fulminant hepatitis and jaundice, with an associated gross accumulation of copper in the liver. This strain is a model for Wilson's Disease (see HEPATOLENTICULAR DEGENERATION). |
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Rats, Inbred Lew |
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Rats, Inbred OLETF - An inbred strain of Long-Evans rats that develops hyperglycemia, hyperinsulinemia, and mild obesity, mostly in males, that resembles non-insulin-dependent diabetes mellitus in humans. It was developed from outbred Long-Evans stock in 1983. |
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Rats, Inbred SHR - A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke. |
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Rats, Inbred WF |
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Rats, Inbred WKY - A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR). |
Rats, Inbred Strains Definitions and Terms
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