Trimethoprim
| Definition: |
A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported. |
| Notes: |
consider TRIMETHOPRIM RESISTANCE for nonsusceptibility of bacteria |
| Also Called: |
Proloprim,Trimpex |
| CAS Type 1 Name: |
CAS Number: |
738-70-5 |
| Previously Indexed: |
Anti-Infective Agents (1966-1971),Folic Acid Antagonists (1966-1971),Pyrimidines (1966-1971) |
Trimethoprim Definitions and Terms
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