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Receptors, Drug

Definition: Proteins that bind specific drugs with high affinity and trigger intracellular changes influencing the behavior of cells. Drug receptors are generally thought to be receptors for some endogenous substance not otherwise specified.
Notes: do not confuse with CHEMORECEPTORS: TN 160; coord IM with specific drug or chemical (IM); DF: RECEPT DRUG
Previously Indexed: Pharmacology (1966-1967)

Receptors, Drug Categories.
Receptors, Phencyclidine - Specific sites or molecular structures on cell membranes or in cells with which phencyclidine reacts or to which it binds to elicit the specific response of the cell to phencyclidine. Studies have demonstrated the presence of multiple receptor sites for PCP. These are the PCP/sigma site, which binds both PCP and psychotomimetic opiates but not certain antipsychotics, and the PCP site, which selectively binds PCP analogs.

Receptors, Drug Definitions and Terms

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