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Antifreeze Proteins

Definition: Proteins that bind to ice and modify the growth of ice crystals. They perform a cryoprotective role in a variety of organisms.
Notes: GEN or unspecified; prefer specific types
Also Called: Antifreeze Glycoproteins
Previously Indexed: Glycoproteins (1983-2000),Peptides (1980-1982)

Antifreeze Proteins Categories.
Antifreeze Proteins, Type I - A subclass of ANTIFREEZE PROTEINS that are 3-5 kD in size and contain a single alanine-rich amphipathic alpha-helix.
Antifreeze Proteins, Type II - A subclass of ANTIFREEZE PROTEINS that have a cystine-rich globular structure of approximately 14 kD.
Antifreeze Proteins, Type III - A subclass of ANTIFREEZE PROTEINS that are globular, 6.5 kD in size and contain compact beta-sheet structures.
Antifreeze Proteins, Type IV - A subclass of ANTIFREEZE PROTEINS that contain four amphipathic alpha-helices folded into an antiparallel helix bundle.

Antifreeze Proteins Definitions and Terms

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