Carcinogens
| Definition: |
Substances that increase the risk of neoplasms in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. |
| Notes: |
D LIST qualif except /adv eff /pois; be careful: "carcinogenic effect" of a drug or chem in dis or clin context is probably neopl term(s) /chem ind + drug or chem named (with required qualif) & not CARCINOGENS; Manual 24.5.6.2+ |
| Also Called: |
Tumor Initiators,Tumor Promoters |
Carcinogens Categories.
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Carcinogens, Environmental - Carcinogenic substances that are found in the environment. |
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Peroxisome Proliferators - A class of nongenotoxic carcinogens that induce the production of hepatic peroxisomes and induce hepatic neoplasms after long-term administration. |
Carcinogens Definitions and Terms
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