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Nitrofurans

Definition:
Notes: urinary anti-infectives

Nitrofurans Categories.
FANFT - A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.
Furagin - Nitrofuran derivative anti-infective agent used for urinary tract infections.
Furazolidone - A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone acts by gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Furylfuramide - Used formerly as antimicrobial food additive. It causes mutations in many cell cultures and may be carcinogenic.
Nifuratel - Local antiprotozoal and antifungal agent that may also be given orally.
Nifurtimox - Possibly effective against parasites. Synonyms: Lampit; Bayer 2502.
Nitrofurantoin - A urinary anti-infective agent effective against most gram-positive and gram-negative organisms. Although sulfonamides and antibiotics are usually the agents of choice for urinary tract infections, nitrofurantoin is widely used for prophylaxis and long-term suppression.
Nitrofurazone - A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections. Nitrofurazone has also been administered orally in the treatment of trypanosomiasis.
Nitrovin - An antibacterial growth promoter used in animal feeds.
SQ-18506 - A nitrovinyl furan used as a schistosomicidal agent and proposed for trypanosomiasis, especially Chagas disease.

Nitrofurans Definitions and Terms

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