Aristolochic Acids
| Definition: |
Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINE) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES). |
| Previously Indexed: |
Phenanthrenes (1965-2002) |
Aristolochic Acids Definitions and Terms
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