Dopamine Agents
| Definition: |
Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. |
| Notes: |
GEN or unspecified; prefer specific groups or specific drugs |
| Previously Indexed: |
Dopamine/metabolism (1966-1988),Receptors, Dopamine (1977-1988) |
Dopamine Agents Categories.
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Dopamine Agonists - Drugs that bind to and activate dopamine receptors. |
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Dopamine Antagonists - Drugs that bind to but do not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. |
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Dopamine Uptake Inhibitors - Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake. |
Dopamine Agents Definitions and Terms
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