Li-Fraumeni Syndrome
| Definition: |
Rare autosomal dominant syndrome characterized by mesenchymal and epithelial neoplasms at multiple sites. A point mutation of the p53 tumor suppressor gene apparently predisposes family members who inherit it to develop certain cancers. |
| Notes: |
a multiple neopl syndrome; do not use /blood supply /chem /congen /second /secret /ultrastruct |
| Previously Indexed: |
Neoplasms (1982-1986),Neoplastic Syndromes, Hereditary (1987-1991),Syndrome (1982-1986) |
Li-Fraumeni Syndrome Definitions and Terms
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