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Neoplasms, Vascular Tissue

Definition: Neoplasms composed of vascular tissue. This concept does not refer to neoplasms located in blood vessels.
Notes: neoplasms composed of vascular tissue, NOT neoplasms located in vascular tissue ( = VASCULAR NEOPLASMS): TN 135; /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM); restricted use: Manual 24.2.2.5

Neoplasms, Vascular Tissue Categories.
Angiofibroma - A benign neoplasm of fibrous tissue in which there are numerous small and large, frequently dilated, vascular channels. (Stedman, 25th ed)
Angiokeratoma - A vascular, horny neoplasm of the skin characterized by TELANGIECTASIS and secondary epithelial changes including acanthosis and hyperkeratosis.
Glomus Tumor - A blue-red, extremely painful vascular neoplasm involving a glomeriform arteriovenous anastomosis (glomus body), which may be found anywhere in the skin, most often in the distal portion of the fingers and toes, especially beneath the nail. It is composed of specialized pericytes (sometimes termed glomus cells), usually in single encapsulated nodular masses which may be several millimeters in diameter (From Stedman, 27th ed). CHEMODECTOMA, a tumor of NEURAL CREST origin, is also sometimes called a glomus tumor.
Hemangioma - An extremely common benign tumor, occurring most commonly in infancy and childhood, made up of newly formed blood vessels, and resulting from malformation of angioblastic tissue of fetal life. It can occur anywhere in the body but is most frequently noticed in the skin and subcutaneous tissues. About 75% are present at birth, and about 60% occur in the head and neck area. The majority in infancy will regress spontaneously. Some hemangiomas grow rapidly during the early months of life and may be a source of some concern, although virtually all disappear by about 5 years of age. They do not metastasize and simple excision will often be curative. (Dorland, 27th ed; from Stedman, 25th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1355)
Hemangiopericytoma - A tumor composed of spindle cells with a rich vascular network, which apparently arises from pericytes, cells of smooth muscle origin that lie around small vessels. Benign and malignant hemangiopericytomas exist, and the rarity of these lesions has led to considerable confusion in distinguishing between benign and malignant variants. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1364)

Neoplasms, Vascular Tissue Definitions and Terms

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