Neoplasms, Gonadal Tissue
| Definition: |
Neoplasms composed of ovarian or testicular tissue. This concept does not refer to neoplasms located in the ovaries or testes. |
| Notes: |
neoplasms composed of gonadal tissue, NOT neoplasms located in the ovaries or testes: TN 135; /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM); restricted use: Manual 24.2.2.5; DF: NEOPL GONADAL TISS |
| Also Called: |
Gynandroblastoma |
Neoplasms, Gonadal Tissue Categories.
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Adrenal Rest Tumor - A rare, usually benign, ovarian tumor thought to be derived from embryonic rest cells of the adrenals. This tumor causes various degrees of masculinization. |
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Androblastoma - A neoplasm arising from the ovarian stroma. It commonly causes defeminization. |
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Granulosa Cell Tumor - An ovarian tumor originating in the cells of the primordial membrana granulosa of the graafian follicle. It may be associated with excessive production of estrogen (ESTROGENS). |
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Leydig Cell Tumor - The most common nongerminal tumor of the testis, derived from the Leydig cells. It is rarely malignant. This tumor appears among 1-3% of testicular tumors and although they may be seen in children, the median age of appearance is 60 years. They are sometimes seen in women as ovarian tumors. Clinically, symptoms are usually related to the endocrine abnormalities induced by this tumor. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1597) |
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Luteoma - A benign ovarian tumor of granulosa or theca-lutein cell origin, producing progesterone effects on the uterine mucosa. (Stedman, 25th ed) |
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Sertoli Cell Tumor - A rare benign tumor of the testis that histologically resembles the fetal testis. There are three varieties: diffuse stromal, mixed (stromal and epithelial), and tubular (epithelial). Sertoli cells in the epithelial elements may produce estrogen and cause feminization. (Dorland, 27th ed) |
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Sex Cord-Stromal Tumor - A malignant neoplasm of the ovary or testis. These tumors differentiate toward sex cords (in embryonic gonads) in the form of female (i.e., granulosa and theca) cells, male (i.e., Sertoli and Leydig) cells, or indifferent elements. In the ovary, sex cord-stromal tumors comprise 5% of all ovarian neoplasms. In the testes, Leydig and Sertoli cell tumors comprise about 5% of all testicular neoplasms, 10% of which behave in a malignant fashion. (From Segen, Dictionary of Modern Medicine, 1992) |
Neoplasms, Gonadal Tissue Definitions and Terms
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