Sirolimus
| Definition: |
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties. |
| Also Called: |
AY 22-989,Rapamune |
| CAS Number: |
53123-88-9 |
| Previously Indexed: |
Polyenes (1976-1998) |
Sirolimus Definitions and Terms
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