Biological Assay
| Definition: |
A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc. |
| Notes: |
assays using living-matter intermediate; check text: not all "bioassays" are MeSH term BIOLOGICAL ASSAY; Manual 22.27; DF: BIOL ASSAY |
Biological Assay Categories.
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Endpoint Determination - Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect. |
Biological Assay Definitions and Terms
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