Platelet-Derived Growth Factor
| Definition: |
Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. |
| Notes: |
/biosyn /physiol permitted; DF: PDGF |
| Previously Indexed: |
Blood Proteins (1977-1983),Growth Substances (1977-1983),Peptides (1977-1983) |
Platelet-Derived Growth Factor Categories.
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Proto-Oncogene Proteins c-sis - Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B chain of PLATELET-DERIVED GROWTH FACTOR. Overexpression of c-sis causes tumorigenesis. |
Platelet-Derived Growth Factor Definitions and Terms
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