Endothelial Growth Factors
| Definition: |
These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences. |
| Also Called: |
alpha-Endothelial Growth Factor,beta-Endothelial Growth Factor |
| Previously Indexed: |
Fibroblast Growth Factor (1984-1990),Growth Substances (1966-1983) |
Endothelial Growth Factors Definitions and Terms
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