Cytokines
| Definition: |
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner. |
| Notes: |
/biosyn /drug eff /physiol /ultrastruct permitted |
| Previously Indexed: |
Biological Factors (1989-1990),Biological Products (1976-1988) |
Cytokines Categories.
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Lymphokines - Soluble protein factors generated by activated lymphocytes that affect other cells, primarily those involved in cellular immunity. |
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Monokines - Soluble mediators of the immune response that are neither antibodies nor complement. They are produced largely, but not exclusively, by monocytes and macrophages. |
Cytokines Definitions and Terms
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