Leukocyte-Adhesion Deficiency Syndrome
| Definition: |
Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection. |
| Notes: |
an immunol defic syndrome; DF: LEUKOCYTE ADHESION DEFIC SYNDROME |
| Previously Indexed: |
Immunologic Deficiency Syndromes (1988-1994),Receptors, Leukocyte-Adhesion/deficiency (1988-1990) |
Leukocyte-Adhesion Deficiency Syndrome Definitions and Terms
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