Estrogen Receptor Modulators
| Definition: |
Substances that possess antiestrogenic actions but can also produce estrogenic effects as well. They act as complete or partial agonist or as antagonist. They can be either steroidal or nonsteroidal in structure. |
| Notes: |
do not confuse with SELECTIVE ESTROGEN RECEPTOR MODULATORS |
Estrogen Receptor Modulators Categories.
 |
Estrogen Antagonists - Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds. |
|
Selective Estrogen Receptor Modulators - A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate the estrogen receptor, but act as either an estrogen agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63) |
Estrogen Receptor Modulators Definitions and Terms
MedicalGlossary.org is designed as a free, browsable resource for all. The medical terms and definitions are not intended to replace medical informaion provided by licensed healthcare professionals. Please see a doctor if you need medical assistance. Don't see the medical term you were researching? Send us an e-mail from our "about us" page. We will do our best to research and classify new medical terms in a timely manner. Our current list of medical terms is over 26,000. Data sources include the U.S. National Library of Medicine, 2004 Medical Subject Headings.
|
