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Heterocyclic Compounds, 3-Ring

Definition:	A class of organic compounds containing three ring structures, one of which is made up of more than one kind of atom, usually carbon plus another atom. The heterocycle may be either aromatic or nonaromatic
Notes:	GEN; prefer specifics; used for mapping supplementary chemicals

Heterocyclic Compounds, 3-Ring Categories.

	Acridines
	Carbazoles
	Dactinomycin - A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)
	Dibenzazepines
	Dibenzothiazepines
	Dibenzothiepins
	Dibenzoxazepines
	Dibenzoxepins
	Phenanthridines
	Phenanthrolines
	Phenazines
	Phenothiazines - Compounds containg dibenzo-1,4-thiazine. Some of them are neuroactive.
	Spectinomycin - An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
	Xanthenes - Compounds with three aromatic rings in linear arrangement with an OXYGEN in the center ring.

Heterocyclic Compounds, 3-Ring Definitions and Terms

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