Dactinomycin
| Definition: |
A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015) |
| Also Called: |
Actinomycin,Cosmegen |
| CAS Type 1 Name: |
CAS Number: |
50-76-0 |
Dactinomycin Definitions and Terms
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