Pyrazines
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do not confuse with PYRIDAZINES |
Pyrazines Categories.
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Amiloride - A pyrazine compound inhibiting sodium reabsorbtion through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) |
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Pyrazinamide - A pyrazine that is used therapeutically as an antitubercular agent. |
Pyrazines Definitions and Terms
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