Growth Substances
| Definition: |
Signal molecules that are involved in the control of cell growth and differentiation. |
| Notes: |
GEN or unspecified: prefer specifics |
| Also Called: |
Mitogens, Endogenous |
Growth Substances Categories.
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Cyclins - Regulatory proteins that function in the cell cycle to activate maturation promoting factor. They complex with p34cdc2 (PROTEIN P34CDC2), the catalytic subunit of MATURATION-PROMOTING FACTOR, and modulate its protein kinase activity. Cyclins themselves have no enzymatic activity. |
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Growth Inhibitors - Endogenous or exogenous substances which inhibit the normal growth of human and animal cells or micro-organisms, as distinguished from those affecting plant growth (= PLANT GROWTH REGULATORS). |
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Hepatocyte Growth Factor - Multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. Its receptor is PROTO-ONCOGENE PROTEIN C-MET. |
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Intercellular Signaling Peptides and Proteins - Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal. |
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Plant Growth Regulators - Any of the hormones produced naturally in plants and active in controlling growth and other functions. There are three primary classes: auxins, cytokinins, and gibberellins. |
Growth Substances Definitions and Terms
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