Eicosanoids
| Definition: |
A class of compounds named after and generally derived from C20 fatty acids (EICOSANOIC ACIDS) that includes PROSTAGLANDINS; LEUKOTRIENES; THROMBOXANES, and HYDROXYEICOSATETRAENOIC ACIDS. They have hormone-like effects mediated by specialized receptors (RECEPTORS, EICOSANOID). |
| Notes: |
GEN or unspecified; prefer specifics |
| Previously Indexed: |
Arachidonic Acids (1967-1989),Fatty Acids, Unsaturated (1973-1989),Leukotrienes (1989),Prostaglandins (1966-1989),Thromboxanes (1978-1989) |
Eicosanoids Categories.
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5,8,11,14-Eicosatetraynoic Acid - A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F(2a). |
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8,11,14-Eicosatrienoic Acid - A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5. |
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Lipoxins - Trihydroxy derivatives of eicosanoic acids. They are primarily derived from arachidonic acid, however eicosapentaenoic acid derivatives also exist. Many of them are naturally occuring mediators of immune regulation. |
Eicosanoids Definitions and Terms
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