Transferases
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Transferases are enzymes transferring a group, for example, the methyl group or a glycosyl group, from one compound (generally regarded as donor) to another compound (generally regarded as acceptor). The classification is based on the scheme "donor:acceptor group transferase". (Enzyme Nomenclature, 1992) EC 2. |
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EC 2. |
Transferases Categories.
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Acyltransferases - Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor, forming either esters or amides. (From Enzyme Nomenclature 1992) EC 2.3. |
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Aldehyde-Ketone Transferases - Enzymes that catalyze the transfer of aldehyde or ketone residues. EC 2.2. |
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Alkyl and Aryl Transferases - A somewhat heterogeneous class of enzymes that catalyze the transfer of alkyl or related groups (excluding methyl groups). EC 2.5. |
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Glycosyltransferases - Enzymes that catalyze the transfer of glycosyl groups to an acceptor. Most often another carbohydrate molecule acts as an acceptor, but inorganic phosphate can also act as an acceptor, such as in the case of PHOSPHORYLASES. Some of the enzymes in this group also catalyze hydrolysis, which can be regarded as transfer of a glycosyl group from the donor to water. Subclasses include the HEXOSYLTRANSFERASES; PENTOSYLTRANSFERASES; SIALYLTRANSFERASES; and those transferring other glycosyl groups. EC 2.4. |
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Nitrogenous Group Transferases - Enzymes that catalyze the transfer of nitrogenous groups, primarily amino groups, from a donor, generally an amino acid, to an acceptor, usually a 2-oxoacid. EC 2.6. |
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One-Carbon Group Transferases - A subclass of transferases that transfer chemical groups containing a single carbon. These include the METHYLTRANSFERASES, the HYDROXYMETHYL AND FORMYL TRANSFERASES, the CARBOXYL AND CARBAMOYL TRANSFERASES, and the AMIDINOTRANSFERASES. EC 2.1. |
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Phosphotransferases - A rather large group of enzymes comprising not only those transferring phosphate but also diphosphate, nucleotidyl residues, and others. These have also been subdivided according to the acceptor group. (From Enzyme Nomenclature, 1992) EC 2.7. |
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Sulfur Group Transferases - Enzymes that catalyze the transfer of sulfur atoms (2.8.1), sulfur groups (2.8.2) or coenzyme A (2.8.3). EC 2.8. |
Transferases Definitions and Terms
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