Pepsinogens
| Definition: |
Proenzymes secreted by chief cells, mucous neck cells, and pyloric gland cells, which are converted into pepsin in the presence of gastric acid or pepsin itself. (Dorland, 28th ed) In humans there are 2 related pepsinogen systems: PEPSINOGEN A (formerly pepsinogen I or pepsinogen) and PEPSINOGEN C (formerly pepsinogen II or progastricsin). Pepsinogen B is the name of a pepsinogen from pigs. |
| Notes: |
do not confuse with PEPSINOGEN see PEPSINOGEN A |
| Also Called: |
Pepsinogen B |
| Previously Indexed: |
Enzyme Precursors (1966-1971),Pepsin (1966-1971),Pepsinogen (1972-1998) |
Pepsinogens Categories.
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Pepsinogen A - This is one of 2 related pepsinogen systems in humans and is also known as pepsinogen. (The other is PEPSINOGEN C.) This includes isozymogens Pg1-Pg5 (pepsinogens 1-5, group I or products of PGA1-PGA5 genes). This is the main pepsinogen found in urine. |
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Pepsinogen C - This is one of the 2 related pepsinogen systems in humans. It is found in prostate and seminal fluid whereas PEPSINOGEN A is not. |
Pepsinogens Definitions and Terms
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