Primate T-lymphotropic virus 1
| Definition: |
A species in the family DELTARETROVIRUS comprising strains of different host species but arising from the same geographic origin. They include HUMAN T-LYMPHOTROPIC VIRUS 1 and SIMIAN T-LYMPHOTROPIC VIRUS 1. |
| Notes: |
infection: coord IM with DELTARETROVIRUS INFECTIONS + TUMOR VIRUS INFECTIONS (IM) if pertinent |
Primate T-lymphotropic virus 1 Categories.
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Human T-lymphotropic virus 1 - A strain of PRIMATE T-LYMPHOTROPIC VIRUS 1 isolated from mature T4 cells in patients with T-lymphoproliferation malignancies. It causes adult T-cell leukemia (LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-1-ASSOCIATED), T-cell lymphoma (LYMPHOMA, T-CELL), and is involved in mycosis fungoides, SEZARY SYNDROME and tropical spastic paraparesis (PARAPARESIS, TROPIC SPASTIC). |
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Simian T-lymphotropic virus 1 - A strain of PRIMATE T-LYMPHOTROPIC VIRUS 2, closely related to the human HTLV-1 virus. The clinical, hematological, and histopathological characteristics of the disease in STLV-infected monkeys are very similar to those of human adult T-cell leukemia. Subgroups include the African green monkey subtype (STLV-I-AGM), for which the nucleotide sequence is 95% homologous with that of HUMAN T-LYMPHOTROPIC VIRUS 1, and the Asian rhesus macaque subtype (STLV-I-MM), for which the nucleotide sequence is 90% homologous with that of HUMAN T-LYMPHOTROPIC VIRUS 1. |
Primate T-lymphotropic virus 1 Definitions and Terms
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