Macrophage Inflammatory Proteins
| Definition: |
Heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of macrophages, these chemokines are produced by a variety of cell types including neutrophils, fibroblasts, and epithelial cells. They likely play a significant role in respiratory tract defenses. |
| Notes: |
heparin-binding proteins; DF: MACROPHAGE INFLAMM PROTEINS |
Macrophage Inflammatory Proteins Categories.
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Macrophage Inflammatory Protein-1 - A chemokine that is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating hematopoiesis. Its two variants, MIP-1alpha and MIP-1beta, are 60% homologous to each other. |
Macrophage Inflammatory Proteins Definitions and Terms
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