Leukomalacia, Periventricular
| Definition: |
Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and COGNITIVE DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1) |
| Notes: |
periventricular refers to the cerebral ventricles |
| Also Called: |
Cystic Periventricular Leukomalacia,Neonatal Cerebral Leukomalacia |
| Previously Indexed: |
Cerebral Hemorrhage (1966-1986),Cerebral Ventricles (1966-1986),Encephalomalacia (1966-1986),Infant, Newborn (1966-1986),Infant, Premature, Diseases (1966-1986) |
Leukomalacia, Periventricular Definitions and Terms
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