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Inclusion Bodies

Definition: A generic term for any circumscribed mass of foreign (e.g., lead or viruses) or metabolically inactive materials (e.g., ceroid or Mallory bodies), within the cytoplasm or nucleus of a cell. Inclusion bodies are in cells infected with certain filtrable viruses, observed especially in nerve, epithelial, or endothelial cells. (Stedman, 25th ed)
Notes: A 11 qualif except /cytol; /genet permitted; for bacteria, coord IM with specific bacterium (IM); for viruses, INCLUSION BODIES, VIRAL is available: see note there
Also Called: Cytoplasmic Inclusions
Previously Indexed: Cytoplasmic Granules (1966-1969)

Inclusion Bodies Categories.
Inclusion Bodies, Viral - An area showing altered staining behavior in the nucleus or cytoplasm of a virus-infected cell. Some inclusion bodies represent "virus factories" in which viral nucleic acid or protein is being synthesized; others are merely artifacts of fixation and staining. One example, Negri bodies, are found in the cytoplasm or processes of nerve cells in animals that have died from rabies.
Intranuclear Inclusion Bodies - Circumscribed masses of foreign or metabolically inactive materials, within the CELL NUCLEUS. Some are VIRAL INCLUSION BODIES.

Inclusion Bodies Definitions and Terms

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