Glycoconjugates
| Definition: |
Carbohydrates covalently linked to a nonsugar moiety (lipids or proteins). The major glycoconjugates are glycoproteins, glycopeptides, peptidoglycans, glycolipids, and lipopolysaccharides. (From Biochemical Nomenclature and Related Documents, 2d ed; From Principles of Biochemistry, 2d ed) |
| Notes: |
GEN: prefer specific glycoconjugate |
| Previously Indexed: |
Glycolipids (1966-1987),Glycopeptides (1971-1987),Glycoproteins (1966-1987),Lipopolysaccharides (1966-1987),Peptidoglycan (1971-1987) |
Glycoconjugates Categories.
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Glycolipids - Any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol (see GLYCERIDES), a sphingoid, a ceramide (CERAMIDES) (N-acylsphingoid) or a prenyl phosphate. (From IUPAC's webpage) |
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Glycopeptides - Proteins which contain carbohydrate groups attached covalently to the polypeptide chain. The protein moiety is the predominant group with the carbohydrate making up only a small percentage of the total weight. |
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Glycoproteins - Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins. |
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Lipopolysaccharides - Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed) |
Glycoconjugates Definitions and Terms
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