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Antineoplastic Agents, Hormonal

Definition: Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)
Notes: consider also NEOPLASMS, HORMONE-DEPENDENT /drug ther
Previously Indexed: Antineoplastic Agents (1966-1995)

Antineoplastic Agents, Hormonal Definitions and Terms

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