Camptothecin
| Definition: |
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity. |
| CAS Type 1 Name: |
CAS Number: |
7689-03-4 |
| Previously Indexed: |
Alkaloids (1966-1972),Antineoplastic Agents (1966-1972) |
Camptothecin Categories.
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Topotecan - An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I. |
Camptothecin Definitions and Terms
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